6:00 -8:00 pm
Tuesdays, January 27 & February 3 2015
Continuing Ed & Conference Center
Instructor: Dr. Brian Engdahl
What happens when the brain, that endlessly complex and fascinating organ, the one that makes us us, becomes damaged or compromised? In this course, participants will gain a comprehensive understanding of injuries and illnesses of the brain, as well as the current advances in research and treatment. We'll examine new strategies and interventions for assessing and treating neurological disorders, such as MEG (magnetoencephalography), a unique neuroimaging technique that is simple (the patient is in a resting state), safe, and short (one minute). Through multimedia presentations and discussions, participants will explore the neural differences in disorders such as PTSD, trauma adaptation, Gulf War illness, and mild traumatic brain injury. We'll also investigate the pathologies of these disorders, as well as advances in treatment and recovery options.
Tuition: $80.00 - For more information, email/call: firstname.lastname@example.org 612-624-4000
(Originally presented Thursday, October 16, 2014)
Co-sponsored by the Department of Psychology and the Institute of Child Development at the University of Minnesota
The search is on for biological markers of mental disorders. Neuroimaging techniques that assess brain function (EEG, PET, MRI) are providing tools in this search. We are using magnetoencephalography (MEG), a unique neuroimaging technique that is simple (task free resting state), safe, short (1 minute), dynamic (based on ongoing activity collected every millisecond) and sensitive to changes in brain communication patterns. MEG allows excellent discrimination between controls and disorder-specific groups. We have studied nearly 2000 subjects. Findings on multiple select groups will be presented, highlighting neural differences in PTSD, trauma adaptation, and posttraumatic growth.
Apostolos P Georgopoulos
Peka Christova's paper "Innovations in Resting-state fMRI and MEG" is 'in press' at the Asian Journal of Physics, Vol. 23, No 5 (2014) 849-857.
Functional magnetic resonance imaging (fMRI) and magneto-encephalography (MEG) are modern imaging techniques that rely on physical phenomena to record brain activity. Both methods are non-invasive and require sophisticated equipment and recording conditions. The biological phenomena upon which they are based are different: fMRI measures the Blood Oxygenation Level-Dependent (BOLD) level, which reflects local hemodynamic changes, whereas MEG directly measures integrated local synaptic activity. The superior temporal resolution of MEG allows the assessment of short temporal interaction between the brain regions. Such assessments can apply to healthy subjects and patients. On the other hand, the superior spatial resolution of fMRI allows the precise localization of brain structures with a detailed inside view of brain connectivity patterns. The resting-state recordings of BOLD and MEG signals were analyzed as time series of each voxel/sensor. To estimate the true correlations between them, the prewhitened time series, called innovations, were used.
Please welcome Chelley Chorn, who will be maintaining the data processing pipeline at the Brain Sciences Center. Chelley is from Minneapolis and holds a BS in Physics with an emphasis in Computation from the University of Minnesota. After graduation, she programmed optical simulation software as a software developer for 3M.