Brian Engdahl, PhD

William L. Anderson Chair in PTSD Research

This is an Endowed Chair established in memory of William L. Anderson, a medic killed in World War II, supporting our work “to better understand, diagnose, treat and prevent PTSD"

Adjunct Professor, Neuroscience, Psychology & Cognitive Sciences, University of Minnesota
Psychologist Clinician Investigator, Minneapolis Veterans Affairs Health Care System

Director, Domenici Research Center for Mental Illness
Brain Sciences Center (11B), VA Health Care System
Minneapolis, Minnesota 55417

ph: 612-467-3033
fax: 612-725-2291

PhD, Counseling Psychology, University of Minnesota
BA, Psychology, University of Minnesota

Predictors of PTSD onset, recovery, and resilience through studies of brain function, genetics, and spirituality. Determining the genetic, immunologic, and brain bases of Gulf War Illness so as to develop scientifically based treatments.


  • Tsilibary E-P, Souto E, James L, Engdahl B, Georgopoulos A (In press) Human immunoglobulin (IgG) neutralizes adverse effects of Gulf War Illness (GWI) serum in neural cultures: Paving the way to immunotherapy for GWI. Journal of Neurology and Neuromedicine Georgopoulos A, James L, Cristova, P, Engdahl B (2018) A two-hit model of the biological origin of posttraumatic stress disorder. Journal of Mental Health and Clinical Psychology. 2(5): 9-14
  • Engdahl B, James L, Miller R, Leuthold A, Lewis S, Carpenter A, Georgopoulos A (2018) Brain function in Gulf War Illness (GWI) and associated mental health comorbidities. Journal of Neurology and Neuromedicine. 3(4) 24-34. https://doi.org/10.29245/2572.942X/2018/4.1198
  • James L, Dolan S, Leuthold A, Engdahl B, Georgopoulos A, Georgopoulos AP (2018) The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women. E-Biomedicine. 35: 288-294. doi: 10.1016/j.ebiom.2018.08.026
  • Georgopoulos A, Tsilibary E, Souto E, James L, Engdahl B, Georgopoulos A (2018) Adverse effects of Gulf War Illness (GWI) serum on neural cultures and their prevention by healthy serum. Journal of Neurology and Neuromedicine, 3(2) 19-27
  • James L, Christova P, Lewis S, Engdahl B, Georgopoulos A, Georgopoulos A (2018) Protective effect of Human Leukocyte Antigen (HLA) allele DRB1*13:02 on age-related brain gray matter volume reduction in healthy women. E-BioMedicine, 29, 31-37
  • Danieli Y, Engdahl B (in press) Multigenerational effects of trauma. In: Post-Traumatic Stress Disorder. C Nemerroff & C Marmar (Eds). Oxford University Press
  • Mattson E, James L, Engdahl B (2018) Personality factors and their impact on PTSD and Post Traumatic Growth is mediated by coping style among OIF/OEF veterans. Military Medicine. 183 (9-10) e475-e480. https://doi.org/10.1093/milmed/usx201
  • Engdahl B. (in press) Post-traumatic stress disorder. Minnesota Health Care News
  • James L, Christova P, Engdahl B, Lewis S, Carpenter A, Georgopoulos A (2017) Human Leukocyte Antigen (HLA) and Gulf War Illness (GWI): HLA protein DRB1*13:02 spares subcortical atrophy in Gulf War veterans. E-BioMedicine. December, 26, 126-131
  • Mattson E, Johnson R, James L, Engdahl B (2017) Predicting Posttraumatic Growth in veterans: The role of coping mechanisms and personality. https://conservancy.umn.edu/handle/11299/187699
  • Georgopoulos AP, James LM, Engdahl BE. Neural mechanisms of posttraumatic stress disorder. Frontiers Research Topic (2017) https://www.frontiersin.org/research-topics/3447/neural-mechanisms-of-posttraumatic-stress-disorder
  • Georgopoulos A, James L, Carpenter A, Engdahl B, Leuthold A, Lewis S. (2017) Gulf War Illness (GWI) as a neuroimmune disease. Experimental Brain Research. 235(10), 3217-3225
  • Georgopoulos A, Christova P, James L, Engdahl B, Carpenter A, Lewis S. (2017) Subcortical brain atrophy in Gulf War Illness. Experimental Brain Research. 235(9), 2777-2786
  • Frankfurt S, Frazier P, Engdahl B. (2017) An empirical investigation of Moral Injury in combat veterans. Military Medicine. 182, e1950-e1956
  • James L, Engdahl B, Georgopoulos A. (2017) Apolipoprotein E: The resilience gene Experimental Brain Research. 235(6), 1853-1859
  • James L, Engdahl B, Leuthold A, Georgopoulos A. (2016) Brain correlates of Human Leukocyte antigen (HLA) protection in Gulf War Illness (GWI) E-Biomedicine. Nov; 72-79
  • Engdahl B, James L, Miller R, Leuthold A, Lewis S, Carpenter A, Georgopoulos A. (2016) A magnetoenephalographic (MEG) study of Gulf War Illness (GWI) E-Biomedicine. 12: 127-132
  • Danieli Y, Norris F, Engdahl B. (2017) A question of who, not if: Psychological disorders in Holocaust survivors’ children. Psychological Trauma. 9(S1). 98-106
  • Danieli Y, Norris F, Engdahl B. (2016) Multigenerational Legacies of Trauma: Modeling the What and How of Transmission. American Journal of Orthopsychiatry, 86(6) 639-651
  • James L, Engdahl B, Leuthold A, Krueger R, Georgopoulos A. (2015) Pathological personality traits modulate neural interactions. Experimental Brain Research, 233(12) 3543–3552
  • Christova P, James L, Engdahl B, Lewis S, Georgopoulos A. (2015) Diagnosis of posttraumatic stress disorder (PTSD) based on correlations of prewhitened fMRI data. Experimental Brain Research. 233(9), 2695-2705
  • James L, Anders S, Peterson C, Engdahl B, Krueger R, Georgopoulos A. (2015) DSM-5 personality traits discriminate between posttraumatic stress disorder and control groups. Experimental Brain Research 233(7), 2021-2028
  • Anders S, Peterson C, James L, Engdahl B, Leuthold A, Georgopoulos A. (2015) Neural communication in posttraumatic growth: Differences between veterans with PTSD and resilient controls. Experimental Brain Research 233(7), 2013-2020
  • Danieli Y, Norris F, Paisner V, Engdahl B, Richter J. (2015) The Danieli Inventory of Multigenerational Legacies of Trauma, Part II: Reparative adaptational impacts. American Journal of Orthopsychiatry. 85, 229-37
  • Danieli Y, Norris F, Lindert J, Paisner V, Kronenberg S, Engdahl B, Richter J. (2015) The Danieli Inventory of Multigenerational Legacies of Trauma, Part I: Posttrauma adaptational styles in their children's eyes. Journal of Psychiatric Research 68, 167-175
  • Harris J, Nienow T, Choi A, Engdahl B (2015) Client report of spirituality in recovery from serious mental illness. Psychology of Religion and Spirituality (American Psychological Association). 7, 142-149
  • Georgopoulos AP, James LM, Mahan MY, Joseph J, Georgopoulos A, Engdahl BE (2015) Reduced Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI). EBioMedicine. doi:10.1016/j.ebiom.2015.11.037
  • Danieli Y, Norris F, Paisner V, Engdahl B, Richter J. (in press) Assessing multigenerational legacies of trauma part I: Posttrauma family adaptational styles. American Journal of Orthopsychiatry
  • Frankfurt S, Anders S, James L, Engdahl B, Winskowski A (2015) Evaluating the dimensionality of PTSD in a sample of OIF/OEF veterans. Psychological Trauma: Theory, Research, Policy and Practice. E-pub ahead of print: 1-19-2015
  • James L, Belitskaya-Lévy I, Lu Y, Wang H, Engdahl B, Leuthold A, Georgopoulos A (2015) Development and application of a diagnostic algorithm for PTSD. Psychiatry Research: Neuroimaging, 231, 1-7
  • Peterson C, James L, Anders S, Engdahl B, Georgopoulos A (2015) The role of apolipoprotein E in the severity of PTSD re-experiencing symptoms. Journal of Neuropsychiatry and Clinical Neuroscience, 27, 1-5
  • Harris J, Erbes C, Engdahl B, Winskowski A & Nguyen X (2014). Social support as a mediator in the relationship between religious comforts and strains and trauma symptoms. Psychology of Religion and Spirituality (American Psychological Association), 6, 223-229
  • James L, Engdahl B, Leuthold A, Lewis S, Van Kampen E, Georgopoulos A. (2013) Differences in Neural Network Modulation by Trauma between Veterans with PTSD and Resilient Controls. JAMA Psychiatry (formerly Archives of General Psychiatry) 70(4), 410-418
  • James L, Van Kampen E, Miller R, Engdahl B (2013) Risk and Protective Factors associated with symptoms of posttraumatic stress, depression, and alcohol misuse in OEF/OIF Veterans chronic PTSD symptoms. Military Medicine. 178(2), 59-65
  • Engdahl B, (2013) What We have Learned from Former Prisoners of War. In B Moore, J Barnett (Eds) Military Psychologists' Desk Reference, Oxford University Press.
  • Harris J, Erbes C, Engdahl B, Ogden H, Olson R, Winskowski A, Campion K, & Mataas S. (2012). Religious distress and coping with stressful life events: A longitudinal study. Journal of Clinical Psychology. 68; 1276-1286.
  • Engdahl B, Stenger C (2012) Serving America’s Former Prisoners of War: Getting it “Right”. In T Miller (Ed) Psychology in the Veterans Administration: A History. Sage
  • Ogden H, Harris J I, Erbes C, Engdahl B, Olson R, Winskowski A M, McMahill J. (2011) Religious functioning and trauma outcomes among combat veterans. Counseling and Spirituality. 30(1); 71-89.
  • Harris J I, Erbes C, Engdahl B, Thuras P, Murray-Swank N, Grace D, Ogden H, Olson R,Winskowski A, Bacon R, Malec C, Campion K, Le T. (2011) The effectiveness of trauma focused spiritually integrated intervention for veterans. Journal of Clinical Psychology. 67, 1-14
  • Engdahl B, Leuthold A, Tan H-R, Lewis S, Winskowski A, Dikel T, Georgopoulos A (2010) Post-traumatic stress disorder: A right temporal lobe syndrome? Journal of Neural Engineering, 7(6); 1-8
  • Georgopoulos A, Tan H-R, Lewis S, Leuthold A, Winskowski A, Lynch J, Engdahl B (2010) The synchronous neural interactions test as a functional biomarker for post-traumatic stress disorder: A robust classification method based on the bootstrap. J Neural Engineering, 7; 1-7. http://iopscience.iop.org/1741-2552/7/1/016011


Updated November 29, 2018