Scott Lewis, M.D., Ph.D.

Principal Investigator, Brain Sciences Center

Staff Physician, Neurology Clinic, Minneapolis VA Medical Center

Assistant Professor, Department of  Neurology, University of Minnesota

functional MRI, MEG, cognitive and motor behavior in health and neurologic disease

Residency, Neurology, University of Michigan

Internship, Internal Medicine, University of Michigan

Ph.D., University of Minnesota, Biochemistry

M.D., University of Minnesota

B.S., University of Minnesota, Biochemistry

Selected publications

James L, Christova P, Lewis S, Engdahl B, Georgopoulos A & Georgopoulos AP (in press) Human Leukocyte Antigen (HLA) allele DRB1*13:02 prevents brain atrophy in “healthy” brain aging. E-Biomedicine

James L, Christova P, Engdahl B, Lewis S, Carpenter A, Georgopoulos A (2017) Human Leukocyte Antigen (HLA) and Gulf War Illness (GWI): HLA protein DRB1*13:02 spares subcortical atrophy in Gulf War veterans. E-BioMedicine. December, 126-131

Georgopoulos A, Christova P, James L, Engdahl B, Carpenter A, Lewis S (2017) Subcortical brain atrophy in Gulf War Illness. Experimental Brain Research. 235(9), 2777-2786

Engdahl B, James L, Miller R, Leuthold A, Lewis S, Carpenter A, Georgopoulos A (2016) A magnetoenephalographic (MEG) study of Gulf War Illness (GWI). E-Biomedicine. 12: 127-132

Lewis S, Vydrová R, Leuthold A, Georgopoulos A (2016) Cortical communication after prenatal exposure to alcohol. Experimental Brian Research. Nov; 234(11), 3347-3353

Christova P, James L, Engdahl B, Lewis S, Georgopoulos A. (2015) Diagnosis of posttraumatic stress disorder (PTSD) based on correlations of prewhitened fMRI data: Outcomes and areas involved. Experimental Brain Research. 233(9), 2695-2705

James L, Engdahl B, Leuthold A, Lewis S, Van Kampen E, Georgopoulos A (2013) Differences in neural network modulation by trauma between veterans with PTSD and resilient controls. JAMA Psychiatry. 70(4), 410-418

Lewis S, Christova P, Jerde T, Georgopoulos A (2012) A compact and realistic cerebral cortical layout derived from prewhitened resting-state fMRI time series: Cherniak's adjacency rule, size law, and metamodule grouping upheld. Frontiers in Neuroanatomy. Sept 6;6:36.

Engdahl B, Leuthold A, Tan H-R, Lewis S, Winskowski A, Dikel T, Georgopoulos A (2010) Post-traumatic stress disorder: A right temporal lobe syndrome? Journal of Neural Engineering, 7(6), 1-8

Georgopoulos A, Tan H-R, Lewis S, Leuthold A, Winskowski A, Lynch J, Engdahl B (2010) The synchronous neural interactions test as a functional biomarker for post-traumatic stress disorder: A robust classification method based on the bootstrap. Journal of Neural Engineering, 7, 1-7

Karageorgiou E, Lewis S, McCarten J, Leuthold A, Hemmy L, McPherson S, Rottunda S, Rubins D, Georgopoulos A (2012) Canonical correlation analysis of synchronous neural interactions and cognitive deficits in Alzheimer's dementia. Journal of Neural Engineering

Alonso A, Koutlas I, Leuthold A, Lewis S, Georgopoulos A (2010) Cortical processing of facial tactile stimuli in temporomandibular disorder as revealed by magnetoencephalography. Experimental Brain Research. 2010 Jul;204(1):33-45

Pardo J, Lee J, Kuskowski M, Munch K, Carlis J, Sheikh S, Surerus C, Lewis S, McCarten J, Fink H, McPherson S, Shah H, Rottunda S, Dysken M (2010) Fluorodeoxyglucose positron emission tomography of mild cognitive impairment with clinical follow-up at 3 years. Alzheimers Dement. Jul;6(4):326-33

Tzagarakis C, Jerde TA, Lewis S, Uğurbil K, Georgopoulos A (2009) Cerebral cortical mechanisms of copying geometrical shapes: a multidimensional scaling analysis of fMRI patterns of activation. Exp Brain Res. 2009 Apr;194(3):369-80

Kimberley TJ, Lewis SM, Strand C, Rice BD, Hall S, Slivnik P (2009) Neural substrates of cognitive load changes during a motor task in subjects with stroke. J Neurol Phys Ther. 2008 Sep;32(3):110-7

Pardo J, Sheikh S, Schwindt G, Lee J, Kuskowski M, Surerus C, Lewis S, Abuzzahab F, Adson D, Rittberg B (2008) Chronic vagus nerve stimulation for treatment-resistant depression decreases resting ventromedial prefrontal glucose metabolism. Neuroimage. 2008 Aug 15;42(2):879-89


Updated December 22, 2017