Matt Chafee, PhD

Principal Investigator, BSC
Assistant Professor of Neuroscience, University of Minnesota
chafe001@umn.edu

Education

PhD, Neurobiology, Yale University
BS, Pyschobiology, Oberlin College

Specialty/Focus

Neural basis of spatial cognition and working memory, cortical system dysfunction in psychiatric disease

Publications

Pages:
1

2018-06-27 through 2007-02-01

•
2

2006-09-01 through 1992-12-01

  1. Zick JL, Blackman R, Crowe D, Amirikian B, DeNicola A, Netoff TI, & Chafee M (2018, June) Blocking NMDAR Disrupts Spike Timing and Decouples Monkey Prefrontal Circuits: Implications for Activity-Dependent Disconnection in Schizophrenia Neuron 98(6) 1243-1255.e5 10.1016/j.neuron.2018.05.010
  2. Kang SS, MacDonald III AW, Chafee M, Im CH, Bernat EM, Davenport ND, & Sponheim S (2018, January) Abnormal cortical neural synchrony during working memory in schizophrenia Clinical Neurophysiology 129(1) 210-221 10.1016/j.clinph.2017.10.024
  3. Chafee M, & Crowe D (2017, October) Implicit and Explicit Learning Mechanisms Meet in Monkey Prefrontal Cortex Neuron 96(2) 256-258 10.1016/j.neuron.2017.09.049
  4. MacDonald III AW, Zick JL, Netoff TI, & Chafee M (2016, December) The Computation of Collapse - Can Reliability Engineering Shed Light on mental Illness? Computational Psychiatry: New Perspectives on mental Illness 153-168
  5. Averbeck B, & Chafee M (2016, October) Using model systems to understand errant plasticity mechanisms in psychiatric disorders Nature Neuroscience 191418-1425 10.1038/nn.4413
  6. Blackman R, Crowe D, DeNicola A, Sakellaridi S, MacDonald III AW, & Chafee M (2016, April) Monkey Prefrontal Neurons Reflect Logical Operations for Cognitive Control in a Variant of the AX Continuous Performance Task (AX-CPT) Journal of Neuroscience 36(14) 4067-4079 10.1523/JNEUROSCI.3578-15.2016
  7. MacDonald III AW, Zick JL, Chafee M, & Netoff TI (2016, January) Integrating Insults: Using Fault Tree Analysis to Guide Schizophrenia Research across Levels of Analysis Frontiers in Human Neuroscience 9a698 10.3389/fnhum.2015.00698
  8. Elshaikh AA, Sponheim S, Chafee M, & MacDonald III AW (2015, May) Spatial attentional control is not impaired in schizophrenia: Dissociating specific deficits from generalized impairments Journal of Abnormal Psychology 235(2) 302-308 10.1037/a0038537
  9. Crowe D, Goodwin SJ, Blackman R, Sakellaridi S, Sponheim S, MacDonald III AW, & Chafee M (2013, September) Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition Nature Neuroscience 161484-1491 10.1038/nn.3509
  10. Blackman R, MacDonald III AW, & Chafee M (2013, May) Effects of Ketamine on Context-Processing Performance in Monkeys: A New Animal Model of Cognitive Deficits in Schizophrenia Neuropsychopharmacology 382090-2100 10.1038/npp.2013.118
  11. Chafee M, & Crowe D (2013, January) Thinking in spatial terms: decoupling spatial representation from sensorimotor control in monkey posterior parietal areas 7a and LIP Frontiers in Integrative Neuroscience 6a112 10.3389/fnint.2012.00112
  12. Chafee M (2013, January) A Scalar Neural Code for Categories in Parietal Cortex: Representing Cognitive Variables as "More" or "Less" Neuron 77(1) 7-9 10.1016/j.neuron.2012.12.025
  13. Goodwin SJ, Blackman R, Sakellaridi S, & Chafee M (2012, March) Executive Control Over Cognition: Stronger and Earlier Rule-Based Modulation of Spatial Category Signals in Prefrontal Cortex Relative to Parietal Cortex Journal of Neuroscience 32(10) 3499-3515 10.1523/JNEUROSCI.3585-11.2012
  14. Kang SS, Sponheim S, Chafee M, & MacDonald III AW (2011, August) Disrupted functional connectivity for controlled visual processing as a basis for impaired spatial working memory in schizophrenia Neuropsychologia 49(10) 2836-2847 10.1016/j.neuropsychologia.2011.06.009
  15. Crowe D, Averbeck B, & Chafee M (2010, September) Rapid Sequences of Population Activity Patterns Dynamically Encode Task-Critical Spatial Information in Parietal Cortex Journal of Neuroscience 30(35) 11640-11653 10.1523/JNEUROSCI.0954-10.2010
  16. Caminiti R, Chafee M, Battaglia-Mayer A, Averbeck B, Crowe D, & Georgopoulos AP (2010, June) Understanding the parietal lobe syndrome from a neurophysiological and evolutionary perspective European Journal of neuroscience 31(12) 2320-2340 10.1111/j.1460-9568.2010.07291.x
  17. Averbeck B, Crowe D, Chafee M, & Georgopoulos AP (2009, March) Differential contribution of superior parietal and dorsal-lateral prefrontal cortices in copying Cortex 45(3) 432-441 10.1016/j.cortex.2008.02.007
  18. Crowe D, Averbeck B, & Chafee M (2008, May) Neural Ensemble Decoding Reveals a Correlate of Viewer- to Object-Centered Spatial Transformation in Monkey Parietal Cortex Journal of Neuroscience 28(20) 5218-5228 10.1523/JNEUROSCI.5105-07.2008
  19. Chafee M, Averbeck B, & Crowe D (2007, December) Representing Spatial Relationships in Posterior Parietal Cortex: Single Neurons Code Object-Referenced Position Cerebral Cortex 17(12) 2914-2932 10.1093/cercor/bhm017
  20. Chafee M, & Ashe J (2007, February) Intelligence in action Nature Neuroscience 10142-143 10.1038/nn0207-142