Neurologic Disease

Brain areas associated with neuropsychological impairments in neurologic disease.

Objectives: To determine the relations between brain anatomy, brain activity, and neuropsychological measures in neurologic disease. 

Research plan and methods We plan to study a broad range of diseases affecting the nervous system, selecting individuals who have lost specific cognitive and/or motor functions.  Subjects will be recruited according to their disease history and symptoms.  They will then undergo cognitive and motor testing to provide quantitative measures of their function.  Finally, this will be related to brain anatomy, as measured by structural MRI, and/or brain activity, as measured by functional MRI, magnetoencephalography (MEG), and/or electroencephalography (EEG).   Comparisons will be made to healthy control subjects.

Ongoing Studies at the Brain Sciences Center

The primary goal of the research at the Brain Sciences Center is to elucidate the dynamic mechanisms of the working brain in health and disease. The neuroscientists at the Brain Sciences Center are working to unlock the mysteries of debilitating neurological diseases, disorders, and addictions. With today's technology, researchers are able to view these dynamic processes of the working brain, and take the first steps toward understanding the mechanisms which may lead to treatment and prevention to help the millions suffering from brain afflictions.

photo of the Brain Sciences Chair logophoto of Brain Sciences ChairThe Brain Sciences Chair

was created by the efforts of a tripartite partnership from private, state and federal sectors including:

American Legion logoThe American Legion Family of Minnesota


U of M logoThe University of Minnesota


VA logoMinneapolis Veterans Affairs Health Care System

This partnership provided funds for an endowed chair in Brain Sciences, as well as office space and general support for the Brain Sciences Center.

Since it opened in 1991, the Center has grown substantially in physical size and personnel. The staff now includes more than 40 people, who come from a variety of academic backgrounds and institutions around the world. All have trained at the Brain Sciences Center on research methods ranging from neurophysiology to brain imaging. This unique blend of people and the integration of many scientific disciplines creates an environment for excellence in research and education.


Updated April 15, 2016