APG studied Medicine and Physiology at the University of Athens in Greece where he obtained his M.D. and Ph.D. degrees. He was trained in neurophysiology by Vernon B. Mountcastle at Johns Hopkins and, after a brief return to Athens, he came back to Johns Hopkins. He ascended the faculty ranks and promoted to Professor of Neuroscience in 1986.He was a member of the Philip Bard Laboratories of Neuro-physiology at the Department of Neuroscience until 1991 when he moved to Minnesota as the American Legion Brain Sciences Chair at the Minneapolis Veterans Affairs Medical Center and the University of Minnesota.