Scott Lewis, MD PhD
Principal Investigator, Brain Sciences CenterBrain Sciences Center (BSC)
Staff Physician, Neurology Clinic, Minneapolis VA Medical CenterVA Medical Center (VAMC)
Assistant Professor, Department of Neurology, University of Minnesota

lewis093@umn.edu

Education
PhD, Biochemistry, University of Minnesota
MD, University of Minnesota
BS, Biochemistry, University of Minnesota

Specialty/Focus
functional MRI, Magnetoencephalography Magnetoencephalography (MEG)A noninvasive technique that detects magnetic fields above the surface of the head produced by postsynaptic potentials in the brain., cognitive and motor behavior in health and neurologic disease

Publications

Pages: 1November 2022 through July 20102July 2010 through April 2002
  1. The Synchronous Neural InteractionsSynchronous Neural Interactions (SNI)Zero-lag partial correlations in pairs of MEG time series and denote the strength and polarity (positive or negative) of neuronal interactions. Anomalies in SNIs as assessed by MEG differentiate psychiatric disorders from healthy brain functioning and can discriminate among various brain diseases. From this research, a highly distinctive, unique PTSD SNI signature characterized by miscommunication of temporal and parietal and/or parieto-occipital right hemispheric areas with other brain areas has emerged. These findings, in addition to the growing research applying MEG to other psychiatric disorders, highlight the utility of MEG in identifying biomarkers of disease and underscore the potential for broader clinical applications of MEG. test as a functional neuromarker for Post-traumatic Stress DisorderPost-traumatic Stress Disorder (PTSD)A complex psychiatric syndrome that develops in response to trauma exposure. Individuals with PTSD experience intrusive recollections or reexperiencing of the traumatic event, avoidance of trauma reminders, emotional numbing, and hyperarousal. In addition, PTSD is associated with high rates of concomitant physical and mental health problems, increased health care use, and impairment in social and occupational functioning. Almost 7% of the general population and up to 30% of veterans meet lifetime criteria for PTSD. Indeed, PTSD is one of the most common psychiatric disorders, representing a significant and costly public health concern.: a robust classification method based on the bootstrap Journal of Neural Engineering (2010, January) Georgopoulos AP, Tan HRM, Lewis S, Leuthold A, Winskowski AM, Lynch J, & Engdahl B